Signal Transduction at Stony Brook

Overview

Signal transduction is the research focus in 40 laboratories at Stony Brook. Although there is no formal graduate program in the area, the faculty teaches an interdepartmental graduate course in signal transduction and gets together biweekly to participate in a Signal Transduction Club. The following links to individual web pages may be useful for students or other faculty interested in signal transduction research at Stony Brook.

Participating Laboratories

Bliska, Jim (Microbiology) bacterial toxins that alter signalling
Bowen, Mark (Physiology) Single molecule spectroscopy; Coordination of post-synaptic glutamate receptor signaling by the MAGUK family of scaffolds
Brown, Debbie (Biochemistry) rafts in membranes
Carpino, Nicholas (Microbiology) Positive and Negative Regulation of T cell Receptor Signaling
Clark, Richard (Dermatology) integrins & PKCs
Colognato, Holly (Pharmacology) Extracellular matrix in the brain: roles during development and during neurodegeneration
Crawford, Howard (Pharmacology)
Fleit, Howard (Pathology) Fc Receptor signalling
Frohman, Michael (Pharmacology) Phospholipase D
Halegoua, Simon (Neurobiology) neuronal signalling
Haltiwanger, Bob (Biocemisty) Role of glycosylation in signaling
Hayman, Michael (Microbiology) growth factor receptors and transcription factors in cancer
Hearing, Pat (Microbiology) Viral molecular genetics; eukaryotic transcriptional regulation
Hsieh, Jen-Chih (Biochemistry), Wnt signaling
Johnson, Roger (Physiology) adenylate cyclase
Kew, Richard (Pathology) leukocyte chemotaxis
Konopka, Jamie (Microbiology) G-protein signalling in yeast
Leatherwood, Janet (Microbiology)Cell cycle control and DNA replication in fission yeast
Lin, Richard (Medicine) kinase signaling and cell proliferation
McLaughlin, Stuart (Physiology) calcium/phospholipid system; membrane proteins
Mackow, Erich (Medicine) Rotavirus and Hantavirus Pathogenesis
Malbon, Craig (Pharmacology) G-protein-linked receptor biology
Marcu, Ken (Biochemistry) NF-kappa-B signaling
Miller, Todd (Physiology) tyrosine kinases
Moll, Ute (Pathology) p53-gene family, apoptosis
Nassar, Nicolas (Physiology) X-ray structures, small G proteins
Pessin, Jeff (Pharmacology), insulin-mediated signaling
Prives, Joav (Pharmacology) neurotransmitter receptors and small G proteins
Rebecchi, Mario (Physiology) phospholipase C-delta
Reich, Nancy (Pathology) native immune defense response
Sampson, Nicole (Chemistry) Fertilin and its receptor
Scarlata, Suzanne (Physiology) membrane proteins, fluorescence, G proteins
Smith, Steve (Biochemistry) NMR membrane proteins
Thomsen, Jerry (Biochemisty) TGFB signaling and vertebrate development
Tsirka, Stella (Pharmacology) neuronal/microglial signaling
Wang, Hsien-Yu (Physiology) G proteins
Zong, Wei-Xing (Microbiology) Molecular regulation of apoptotic and necrotic cell death

Signal Transduction Club

Signal Transduction Club is an informal biweekly meeting of Stony Brook faculty with interests in cell signaling. Meetings, which are Thursday evenings at 5:30 p.m., comprise informal presentations by a member that focus on recent work from his or her laboratory and related research in the field. Signal Transduction Club is organized by Todd Miller (Physiology and Biophysics). Contact Todd (todd.miller@stonybrook.edu) if you are interested in being placed on the mailing list.

Interdepartmental Signal Transduction Graduate Course

This course (HBY553) is taught by about a dozen faculty and provides an interdisciplinary overview of biochemical, biophysical, cell biological, structural and pharmacological approaches to elucidating signal transduction mechanisms and effects. The course is offered in the Spring Semester every other year (odd-numbered years). Enrollment is open to second year graduate students who have taken graduate courses in Biochemistry and Cell Biology, or with permission of the course director.

Research and Clinical Signal Transduction Faculty

In addition to the names listed above, many Research and Clinical faculty are also involved in signal transduction research.: send an email to Stuart.McLaughlin@stonybrook.edu (with a one line description of your work, your departmental affiliation, and a link to your web page if you would like to be included in this list).